The man is being flown to John Hunter Hospital, Newcastle with possible chest injuries.
The Westpac Rescue Helicopter has been called to Possum Brush following a motor vehicle accident.
According to Westpac Rescue Helicopter community liaison officer, Graham Nickisson a 47-year-old man has come off his motorcycle and hit a tree.
Initial reports indicate the man sustained serious injuries.
Multiple emergency personnel also are attending the scene.
Further information will be passed on when it becomes available.